HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tolylboronic acid → 3-Methylsulfanyl-6-(1,2,3,6-tetrahydro-pyridin-4-yl)-1-p-tolyl-1H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tolylboronic acid | HCID 79799 | — |
| Reactant | 4-(3-Methylsulfanyl-1H-indazol-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester | HCID 67447024 | — |
| Product | 3-Methylsulfanyl-6-(1,2,3,6-tetrahydro-pyridin-4-yl)-1-p-tolyl-1H-indazole | HCID 56670164 | — |
Reaction Steps
The title compound was prepared as a white solid by coupling 4-(3-methylsulfanyl-1H-indazol-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester and 4-methyl-phenyl boronic acid to yield an intermediate, which was de-protected to remove the N-Boc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822447B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-1c71e4015de942d7885b98e66c4471ea |
| Source note | uspto-grants-2014_09 |