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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 687671Generated: November 1, 2026

Diethyl Ether → Ethyl 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate

https://huagongshe.com/reaction/687671

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantPiperazineHCID 4837—
ReactantDichloromethaneHCID 6344—
ReactantEthyl 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-7-(2,4,6-triisopropylbenzenesulfonyloxy)-1,8-naphthyridine-3-carboxylateHCID 13849335—
ProductEthyl 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylateHCID 13849334—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-97aae9b498a14c2193b9cdd4a91d27b7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)