Cyclopropylamine → HCID 68289599, compound

HRID 68774Notes

Reaction equation

HRID 68774 reaction equation
[CH2:1]([C:4]1[N:8]=[C:7]([N:9]2[CH2:14][CH2:13][C:12](=O)[CH2:11][CH2:10]2)[O:6][N:5]=1)[CH2:2][CH3:3].[CH:16]1([NH2:19])[CH2:18][CH2:17]1>>[CH:16]1([NH:19][CH:12]2[CH2:13][CH2:14][N:9]([C:7]3[O:6][N:5]=[C:4]([CH2:1][CH2:2][CH3:3])[N:8]=3)[CH2:10][CH2:11]2)[CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 682899031-(3-Propyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-one

Product 1

HCID 68289599HCID 68289599, compound

Procedure

The title compound is prepared as its hydrochloride salt from 1-(3-propyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-one and cyclopropylamine following a procedure analogous to that described in Intermediate 7. LC (method 13): tR=0.79 min; Mass spectrum (ESI+): m/z=251 [M+H]+.

Sources & evidence

ORD record
ord-ca543908830449eabb5b6116a00fff0e
Source dataset
uspto-grants-2014_09
Patent number
US08822471B2

Reaction notes

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