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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 687747Generated: October 30, 2026

Tetrahydrofuran → Methyl 1-(3-fluoro-4-(2-(trimethylsilyl)ethynyl)benzyl)azetidine-3-carboxylate

https://huagongshe.com/reaction/687747

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-(4-(5-Butoxybenzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acidHCID 16737130—
ReactantMethyl 1-(4-bromo-3-fluorobenzyl)azetidine-3-carboxylateHCID 59651823—
ProductMethyl 1-(3-fluoro-4-(2-(trimethylsilyl)ethynyl)benzyl)azetidine-3-carboxylateHCID 59651825—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-9d49693fa6684afa9c76d9b6b4d2a033
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)