2-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-one → 5-[3-Chloro-1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(2-hydroxymethyl-morpholin-4-yl)-thiazol-4-one

HRID 687757Notes

Reaction equation

HRID 687757 reaction equation
[Cl:1][c:2]1[n:3][n:4]([CH2:13][c:14]2[c:15]([C:21]([F:22])([F:23])[F:24])[cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[c:5]2[cH:6][cH:7][c:8]([CH:11]=[O:12])[cH:9][c:10]12.[OH:25][CH2:26][CH:27]1[O:28][CH2:29][CH2:30][N:31]([C:33]2=[N:37][C:36](=[O:38])[CH2:35][S:34]2)[CH2:32]1>>[Cl:1][c:2]1[n:3][n:4]([CH2:13][c:14]2[c:15]([C:21]([F:22])([F:23])[F:24])[cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[c:5]2[cH:6][cH:7][c:8]([CH:11]=[C:35]3[S:34][C:33]([N:31]4[CH2:30][CH2:29][O:28][CH:27]([CH2:26][OH:25])[CH2:32]4)=[N:37][C:36]3=[O:38])[cH:9][c:10]12

Participants

3

Reactant 2

HCID 672406862-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-oneHCID 866545953-Chloro-1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

Product 1

HCID 672405485-[3-Chloro-1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(2-hydroxymethyl-morpholin-4-yl)-thiazol-4-one

Sources & evidence

ORD record
ord-9021d91c5cc0489c9f8a45bb06454a0b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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