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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 68779Generated: October 27, 2026

Cyclopropylamine → N-cyclopropyl-1-(5-ethylpyrazin-2-yl)piperidin-4-amine

https://huagongshe.com/reaction/68779

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
Reactant1-(5-Ethyl-pyrazin-2-yl)-piperidin-4-oneHCID 68290037—
ProductN-cyclopropyl-1-(5-ethylpyrazin-2-yl)piperidin-4-amineHCID 68289603—

Reaction Steps

The title compound is prepared from 1-(5-ethyl-pyrazin-2-yl)-piperidin-4-one and cyclopropylamine following a procedure analogous to that described in Intermediate 7. LC (method 1): tR=0.65 min; Mass spectrum (ESI+): m/z=247 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822471B2
Source datasetuspto-grants-2014_09
ORD IDord-e4de340d33be44bf8664358b3abed589
Source noteuspto-grants-2014_09