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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 687792Generated: October 25, 2026

Tetrahydrofuran → 1-(5-Tert-butyl-2-(1-(2-(dimethylamino)ethyl)-3,3-dimethyl-2-oxopiperazine-4-carbonyl)thiophen-3-yl)-3-(2,3-dichlorophenyl)urea

https://huagongshe.com/reaction/687792

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
Reactant1,2-Dichloro-3-isocyanatobenzeneHCID 33050—
Reactant4-(4-Amino-2-tert-butylthiophene-5-carbonyl)-1-(2-(dimethylamino)ethyl)-3,3-dimethylpiperazin-2-oneHCID 58679123—
Product1-(5-Tert-butyl-2-(1-(2-(dimethylamino)ethyl)-3,3-dimethyl-2-oxopiperazine-4-carbonyl)thiophen-3-yl)-3-(2,3-dichlorophenyl)ureaHCID 58679405—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-7082402900604d9cbe0e47803a1e2b85
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)