4-Bromobenzenesulfonamide → 4-[5-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-benzenesulfonamide

HRID 687814Notes

Reaction equation

HRID 687814 reaction equation
[Br:23][c:24]1[cH:25][cH:26][c:27]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:28][cH:29]1.[Cl:1][c:2]1[c:3]([CH3:22])[cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]([F:15])[F:16])[cH:13]2)[n:17][cH:18][c:19]3[C:20]#[CH:21])[cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([CH3:22])[cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH:14]([F:15])[F:16])[cH:13]2)[n:17][cH:18][c:19]3[C:20]#[C:21][c:24]2[cH:25][cH:26][c:27]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:28][cH:29]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 696964-BromobenzenesulfonamideHCID 866080845-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-3-ethynyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 118526194-[5-(4-Chloro-3-methyl-phenyl)-7-difluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-benzenesulfonamide

Sources & evidence

ORD record
ord-8027cf38edba4b868ec802c0af09c692
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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