4-Hydroxy-4-thiazol-2-yl-cyclohexanone → N-{[1-(4-Hydroxy-4-thiazol-2-yl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-2,5-bis-trifluoromethyl-benzamide
Reaction equation
[NH:14]1[CH2:15][CH:16]([NH:18][C:19](=[O:20])[CH2:21][NH:22][C:23]([c:24]2[c:25]([C:34]([F:35])([F:36])[F:37])[cH:26][cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]2)=[O:38])[CH2:17]1.[OH:1][C:2]1([c:9]2[s:10][cH:11][cH:12][n:13]2)[CH2:3][CH2:4][C:5](=[O:8])[CH2:6][CH2:7]1>>[OH:1][C:2]1([c:9]2[s:10][cH:11][cH:12][n:13]2)[CH2:3][CH2:4][CH:5]([N:14]2[CH2:15][CH:16]([NH:18][C:19](=[O:20])[CH2:21][NH:22][C:23]([c:24]3[c:25]([C:34]([F:35])([F:36])[F:37])[cH:26][cH:27][c:28]([C:30]([F:31])([F:32])[F:33])[cH:29]3)=[O:38])[CH2:17]2)[CH2:6][CH2:7]1Participants
3
Sources & evidence
- ORD record
- ord-27943ae6693844d4b17de3d221ba2129
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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