HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → N-cyclopropyl-1-(5-methylpyrimidin-2-yl)piperidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | 1-(5-Methylpyrimidin-2-yl)piperidin-4-one | HCID 63208322 | — |
| Product | N-cyclopropyl-1-(5-methylpyrimidin-2-yl)piperidin-4-amine | HCID 68290030 | — |
Reaction Steps
The title compound is prepared from 1-(5-methyl-pyrimidin-2-yl)-piperidin-4-one and cyclopropylamine following a procedure analogous to that described in Intermediate 7. LC (method 1): tR=0.55 min; Mass spectrum (ESI+): m/z=233 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-f347b800d17645f4a4f4b302a247f1ba |
| Source note | uspto-grants-2014_09 |