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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 687858Generated: October 25, 2026

1,4-Dioxane → 4-{3-[5-Chloro-4-(4-cyclopropylcarbamoylbenzo[b]thiophen-2-yl)-pyrimidin-2-ylamino]-propyl}-4-ethylpiperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/687858

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-(3-Aminopropyl)-4-ethylpiperidine-1-carboxylic acid tert-butyl esterHCID 68856742—
Reactant2-(2,5-Dichloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamideHCID 86625351—
Product4-{3-[5-Chloro-4-(4-cyclopropylcarbamoylbenzo[b]thiophen-2-yl)-pyrimidin-2-ylamino]-propyl}-4-ethylpiperidine-1-carboxylic acid tert-butyl esterHCID 68856860—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-4aae6307b1cc4b99abf8f6b748056feb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)