Methyl 6-chloro-4-(trifluoromethyl)nicotinate → Methyl 6-[2-(3-methoxypropyl)phenyl]-4-(trifluoromethyl)nicotinate

HRID 687898Notes

Reaction equation

HRID 687898 reaction equation
[CH3:16][O:17][CH2:18][CH2:19][CH2:20][c:21]1[c:22]([B:27]([OH:28])[OH:29])[cH:23][cH:24][cH:25][cH:26]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[c:10]([C:12]([F:13])([F:14])[F:15])[cH:11]1>>[c:2]1(-[c:22]2[c:21]([CH2:20][CH2:19][CH2:18][O:17][CH3:16])[cH:26][cH:25][cH:24][cH:23]2)[n:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[c:10]([C:12]([F:13])([F:14])[F:15])[cH:11]1

Participants

3

Reactant 2

HCID 2775340Methyl 6-chloro-4-(trifluoromethyl)nicotinateHCID 58083347[2-(3-Methoxypropyl)phenyl]boronic acid

Product 1

HCID 67447798Methyl 6-[2-(3-methoxypropyl)phenyl]-4-(trifluoromethyl)nicotinate

Sources & evidence

ORD record
ord-f095c0c41cbd4afca1d8057bca5e7096
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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