HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → Cyclopropyl-(3'-fluoro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | HCID 68289579 | HCID 68289579 | — |
| Product | Cyclopropyl-(3'-fluoro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-amine | HCID 68289864 | — |
Reaction Steps
The title compound is prepared from 1-(3-fluoro-5-trifluoromethyl-pyridin-2-yl)-piperidin-4-one and cyclopropylamine following a procedure analogous to that described for Intermediate 66.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-bbd096257b6547ab813b2468da0de363 |
| Source note | uspto-grants-2014_09 |