N-(1-Cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide → N-Cyclopropyl-N-[1-(3-methoxymethyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide

Participants

Role	Name	HCID	Charge
Reactant	N-(1-Cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide	HCID 86678209	—
Reactant	HCID 178496050	HCID 178496050	—
Product	N-Cyclopropyl-N-[1-(3-methoxymethyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide	HCID 68351849	—

Reaction Steps

The title compound is prepared from N-(1-cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide and N-hydroxy-2-methoxy-acetamidine following a procedure analogous to that described in Example 1. LC (method 6): tR=1.61 min; Mass spectrum (ESI+): m/z=424 [M+H]+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08822471B2
Source dataset	uspto-grants-2014_09
ORD ID	ord-f8f64355d0c642c29843034be17077d9
Source note	uspto-grants-2014_09