Dichloromethane → 6-(3,4-Difluorophenyl)-1-(3-imidazol-1-yl-propylcarbamoyl)-4-methyl-2-oxo-1,2,3,6-tetrahydro-pyrimidine-5-carboxylic Acid Methyl Ester
Reaction equation
[Cl:42][CH2:43][Cl:44].[F:1][c:2]1[cH:3][c:4]([CH:9]2[C:10]([C:29](=[O:30])[O:31][CH3:32])=[C:11]([CH3:28])[NH:12][C:13](=[O:27])[N:14]2[C:15](=[O:16])[O:17][c:18]2[cH:19][cH:20][c:21]([N+:22]([O-:23])=[O:24])[cH:25][cH:26]2)[cH:5][cH:6][c:7]1[F:8].[NH2:33][CH2:34][CH2:35][CH2:36][n:37]1[cH:38][n:39][cH:40][cH:41]1>>[F:1][c:2]1[cH:3][c:4]([CH:9]2[C:10]([C:29](=[O:30])[O:31][CH3:32])=[C:11]([CH3:28])[NH:12][C:13](=[O:27])[N:14]2[C:15](=[O:16])[NH:33][CH2:34][CH2:35][CH2:36][n:37]2[cH:38][n:39][cH:40][cH:41]2)[cH:5][cH:6][c:7]1[F:8]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-ab6700bae8164edcb4f08f2640bfeccb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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