N-(1-Cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide → N-{1-[3-(3-Bromo-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-4-yl}-N-cyclopropyl-4-oxazol-5-yl-benzamide

Participants

Role	Name	HCID	Charge
Reactant	N-(1-Cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide	HCID 86678209	—
Reactant	HCID 178513280	HCID 178513280	—
Product	N-{1-[3-(3-Bromo-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-4-yl}-N-cyclopropyl-4-oxazol-5-yl-benzamide	HCID 68351776	—

Reaction Steps

The title compound is prepared from N-(1-cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide and 3-bromo-N-hydroxy-benzamidine following a procedure analogous to that described in Example 1. LC (method 6): tR=2.09 min; Mass spectrum (ESI+): m/z=534/536 (Br) [M+H]+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08822471B2
Source dataset	uspto-grants-2014_09
ORD ID	ord-a7fe47308505469b81f2e0663fb57a55
Source note	uspto-grants-2014_09