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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 688199Generated: October 25, 2026

Acetate → Methyl 5-(4-fluorophenyl)-6-hydroxynicotinate

https://huagongshe.com/reaction/688199

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetateHCID 175—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantDiisopropylamineHCID 7912—
ReactantAllyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 105144—
Reactant4-Fluorophenylboronic acidHCID 285645—
ReactantMethyl 5-bromo-6-hydroxynicotinateHCID 2764315—
ReactantTris(3-sulfonatophenyl) phosphineHCID 3675707—
ProductMethyl 5-(4-fluorophenyl)-6-hydroxynicotinateHCID 67339481—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-2c9f163dae494ee0ba011a3459644cab
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)