HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyrimidine → N-cyclopropyl-4-oxazol-5-yl-N-(1-pyrimidin-2-ylpiperidin-4-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | N-Cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide | HCID 68289931 | — |
| Product | N-cyclopropyl-4-oxazol-5-yl-N-(1-pyrimidin-2-ylpiperidin-4-yl)benzamide | HCID 68290505 | — |
Reaction Steps
The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 2-chloro-pyrimidine following a procedure analogous to that described in Example 19. LC (method 5): tR=1.89 min; Mass spectrum (ESI+): m/z=390 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-889c6780fea3443183750ed15d180ba5 |
| Source note | uspto-grants-2014_09 |