HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 688213Generated: October 29, 2026
Ethanol → 4-(2,5-Difluorobenzyl)-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1,2,3,4-tetrahydro-[1,8]naphthyridine
https://huagongshe.com/reaction/688213
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium ion | HCID 923 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Carbonate Ion | HCID 19660 | — |
| Reactant | 1-Methyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine | HCID 2769618 | — |
| Reactant | 6-Bromo-4-(2,5-difluorobenzyl)-1,2,3,4-tetrahydro-[1,8]naphthyridine | HCID 57885800 | — |
| Reactant | HCID 178420554 | HCID 178420554 | — |
| Product | 4-(2,5-Difluorobenzyl)-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1,2,3,4-tetrahydro-[1,8]naphthyridine | HCID 46906715 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
|---|
| ORD ID | ord-a0af75cff9e14bcb82d60300c1492e49 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
|---|
