HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-fluoropyridine → N-Cyclopropyl-N-[1-(5-fluoro-pyridin-2-yl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-fluoropyridine | HCID 2782801 | — |
| Reactant | N-Cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide | HCID 68289931 | — |
| Product | N-Cyclopropyl-N-[1-(5-fluoro-pyridin-2-yl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide | HCID 68290596 | — |
Reaction Steps
The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 2-chloro-5-fluoro-pyridine following a procedure analogous to that described in Example 19. LC (method 5): tR=1.79 min; Mass spectrum (ESI+): m/z=407 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-57d1ca9d77fc424e82bded99e2e72c0b |
| Source note | uspto-grants-2014_09 |