5-Chloro-3-(4-methoxyphenyl)-1,2,4-oxadiazole → N-Cyclopropyl-N-{1-[3-(4-methoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-4-yl}-4-oxazol-5-yl-benzamide

Participants

Reaction Steps

The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 5-chloro-3-(4-methoxy-phenyl)-[1,2,4]oxadiazole following a procedure analogous to that described in Example 19 using N-methylpyrrolidinone as solvent. LC (method 6): tR=1.92 min; Mass spectrum (ESI+): m/z=486 [M+H]+.

Provenance & Evidence