HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → N-Cyclopropyl-N-[1-(5-ethyl-[1,2,4]oxadiazol-3-yl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | HCID 178513431 | HCID 178513431 | — |
| Product | N-Cyclopropyl-N-[1-(5-ethyl-[1,2,4]oxadiazol-3-yl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide | HCID 68351847 | — |
Reaction Steps
The title compound is prepared from N-cyclopropyl-N-[1-(N-hydroxycarbamimidoyl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide and propionyl chloride following a procedure analogous to that described in Example 47. LC (method 3): tR=1.83 min; Mass spectrum (ESI+): m/z=408 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-5a2bb96b396c41388b85bea81232f762 |
| Source note | uspto-grants-2014_09 |