HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclobutanecarbonyl chloride → N-[1-(5-Cyclobutyl-[1,2,4]oxadiazol-3-yl)-piperidin-4-yl]-N-cyclopropyl-4-oxazol-5-yl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclobutanecarbonyl chloride | HCID 78705 | — |
| Reactant | HCID 178513431 | HCID 178513431 | — |
| Product | N-[1-(5-Cyclobutyl-[1,2,4]oxadiazol-3-yl)-piperidin-4-yl]-N-cyclopropyl-4-oxazol-5-yl-benzamide | HCID 68351799 | — |
Reaction Steps
The title compound is prepared from N-cyclopropyl-N-[1-(N-hydroxycarbamimidoyl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide and cyclobutanecarbonyl chloride following a procedure analogous to that described in Example 47. LC (method 2): tR=1.27 min; Mass spectrum (ESI+): m/z=434 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822471B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-d940fddcb6a94b3e9d31c9ecd2691295 |
| Source note | uspto-grants-2014_09 |