Dichloromethane → 3-[4-[1-(4-Fluorophenyl)-5-(2-methyltetrazol-5-yl)-1H-indol-3-yl]-1,2,3,6-tetrahydropyridin-1-yl]propionitril

HRID 688693Notes

Reaction equation

HRID 688693 reaction equation
[C:29]([CH:30]=[CH2:31])#[N:32].[Cl:33][CH2:34][Cl:35].[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][c:10]([C:23]3=[CH:28][CH2:27][NH:26][CH2:25][CH2:24]3)[c:11]3[cH:12][c:13](-[c:17]4[n:18][n:19][n:20]([CH3:22])[n:21]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][c:10]([C:23]3=[CH:28][CH2:27][N:26]([CH2:31][CH2:30][C:29]#[N:32])[CH2:25][CH2:24]3)[c:11]3[cH:12][c:13](-[c:17]4[n:18][n:19][n:20]([CH3:22])[n:21]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 7855AcrylonitrileHCID 181772261-(4-fluorophenyl)-5-(2-methyl-5-tetrazolyl)-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole

Product 1

HCID 181772163-[4-[1-(4-Fluorophenyl)-5-(2-methyltetrazol-5-yl)-1H-indol-3-yl]-1,2,3,6-tetrahydropyridin-1-yl]propionitril

Sources & evidence

ORD record
ord-564e1dd4f81d453a8a3398e6ceb2f8fe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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