4-(5-Methyl-1H-1,2,4-triazol-1-yl)benzoic acid → N-Cyclopropyl-N-(3'-fluoro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-4-(5-methyl-[1,2,4]triazol-1-yl)-benzamide

Participants

Reaction Steps

The title compound is prepared from cyclopropyl-(3′-fluoro-5′-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-yl)-amine and 4-(5-methyl-[1,2,4]triazol-1-yl)-benzoic acid following a procedure analogous to that described in Example 90. LC (method 19): tR=4.54 min; Mass spectrum (ESI+): m/z=489 [M+H]+.

Provenance & Evidence