3-fluoro-4-(1H-1,2,4-triazol-1-yl)benzoic acid → N-Cyclopropyl-3-fluoro-N-(3'-fluoro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-4-[1,2,4]triazol-1-yl-benzamide

Participants

Reaction Steps

The title compound is prepared from cyclopropyl-(3′-fluoro-5′-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-yl)-amine and 3-fluoro-4-[1,2,4]triazol-1-yl-benzoic acid following a procedure analogous to that described in Example 90. LC (method 19): tR=4.44 min; Mass spectrum (ESI+): m/z=493 [M+H]+.

Provenance & Evidence