Tert-butyl 3-(6-methoxy-3-pyridinyl)-3a,4,6,6a-tetrahydropyrrolo[3,4-d][1,2]oxazole-5-carboxylate → Tert-butyl 3-[6-(trifluoromethyl)pyridin-3-yl]-3a,4,6,6a-tetrahydropyrrolo[3,4-d][1,2]oxazole-5-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]2[C:11]([c:16]3[cH:17][n:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)=[N:12][O:13][CH:14]2[CH2:15]1.[OH:24][N:25]=[C:26]([Cl:27])[c:28]1[cH:29][n:30][c:31]([C:33]([F:34])([F:35])[F:36])[cH:32][cH:37]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]2[C:11]([c:16]3[cH:17][n:18][c:19]([C:33]([F:34])([F:35])[F:36])[cH:20][cH:21]3)=[N:12][O:13][CH:14]2[CH2:15]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2c5fe69b2140480299e794f1429a1575
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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