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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 689023Generated: October 26, 2026

Dichloromethane → 3-(3,5-Difluorophenyl)-1-[4-(hydroxymethyl)piperidin-1-yl]prop-2-en-1-one

https://huagongshe.com/reaction/689023

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
ReactantBenzotriazol-1-yloxy-tris(dimethylamino)phosphoniumHCID 124335—
Reactant4-PiperidinemethanolHCID 420771—
Reactant3-(3,5-Difluorophenyl)acrylic acidHCID 522810—
Product3-(3,5-Difluorophenyl)-1-[4-(hydroxymethyl)piperidin-1-yl]prop-2-en-1-oneHCID 66938101—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-0fd5de74fd8e4824bad5fe9fffaf281b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)