1-(5-chloropyrimidin-2-yl)-N-cyclopropylpiperidin-4-amine → N-[1-(5-Chloro-pyrimidin-2-yl)-piperidin-4-yl]-N-cyclopropyl-3-fluoro-4-(5-methyl-[1,2,4]triazol-1-yl)-benzamide

Participants

Reaction Steps

The title compound is prepared from [1-(5-chloro-pyrimidin-2-yl)-piperidin-4-yl]-cyclopropyl-amine and 3-fluoro-4-(5-methyl-[1,2,4]triazol-1-yl)-benzoic acid following a procedure analogous to that described in Example 107. LC (method 19): tR=3.90 min; Mass spectrum (ESI+): m/z=456 [M+H]+.

Provenance & Evidence