3-Fluoro-4-(5-methyl-tetrazol-1-yl)-benzoic acid → N-Cyclopropyl-3-fluoro-N-(3'-fluoro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2]bipyridinyl-4-yl)-4-(5-methyl-tetrazol-1-yl)-benzamide

Participants

Reaction Steps

The title compound is prepared from cyclopropyl-(3′-fluoro-5′-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-yl)-amine and 3-fluoro-4-(5-methyl-tetrazol-1-yl)-benzoic acid following a procedure analogous to that described in Example 107. LC (method 19): tR=4.58 min; Mass spectrum (ESI+): m/z=508 [M+H]+.

Provenance & Evidence