Methanol → tert-Butyl 3-(((4'-fluorobiphenyl-4-yl)methylamino)methyl)benzylcarbamate
Reaction equation
[BH4-:33].[CH3:35][OH:36].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([CH:14]=[O:15])[cH:12][cH:13]2)[cH:6][cH:7]1.[NH2:16][CH2:17][c:18]1[cH:19][c:20]([CH2:21][NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[cH:30][cH:31][cH:32]1.[Na+:34]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][NH:16][CH2:17][c:18]3[cH:19][c:20]([CH2:21][NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[cH:30][cH:31][cH:32]3)[cH:12][cH:13]2)[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-b9629e1ef86e48f1b494d98e31c809a8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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