Pyridine-3-sulfonyl chloride → N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(4-morpholinyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-3-pyridinesulfonamide

HRID 689580Notes

Reaction equation

HRID 689580 reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:19]3[c:20]([F:26])[c:21]([NH2:22])[cH:23][cH:24][cH:25]3)[n:10][c:11]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[s:12]2)[n:7]1.[n:27]1[cH:28][c:29]([S:33](=[O:34])(=[O:35])[Cl:36])[cH:30][cH:31][cH:32]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:19]3[c:20]([F:26])[c:21]([NH:22][S:33]([c:29]4[cH:28][n:27][cH:32][cH:31][cH:30]4)(=[O:34])=[O:35])[cH:23][cH:24][cH:25]3)[n:10][c:11]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[s:12]2)[n:7]1

Participants

3

Reactant 2

HCID 3164136Pyridine-3-sulfonyl chlorideHCID 579897213-(5-(2-Chloropyrimidin-4-yl)-2-morpholinothiazol-4-yl)-2-fluoroaniline

Product 1

HCID 57989773N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(4-morpholinyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-3-pyridinesulfonamide

Sources & evidence

ORD record
ord-e162da81146848f4a3cedee0014ed645
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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