4-Bromo-1-isoquinolinamine → 2-(1-((2-(1-aminoisoquinolin-4-yl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol
Reaction equation
[Br:41][c:42]1[cH:43][n:44][c:45]([NH2:52])[c:46]2[cH:47][cH:48][cH:49][cH:50][c:51]12.[CH3:1][n:2]1[c:3]2[n:4][c:5]([Sn:28]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:33][CH2:34][CH2:35][CH3:36])[CH2:37][CH2:38][CH2:39][CH3:40])[n:6][c:7]([N:22]3[CH2:23][CH2:24][O:25][CH2:26][CH2:27]3)[c:8]2[n:9][c:10]1[CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([C:18]([CH3:19])([CH3:20])[OH:21])[CH2:16][CH2:17]1>>[CH3:1][n:2]1[c:3]2[n:4][c:5](-[c:42]3[cH:43][n:44][c:45]([NH2:52])[c:46]4[cH:47][cH:48][cH:49][cH:50][c:51]34)[n:6][c:7]([N:22]3[CH2:23][CH2:24][O:25][CH2:26][CH2:27]3)[c:8]2[n:9][c:10]1[CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([C:18]([CH3:19])([CH3:20])[OH:21])[CH2:16][CH2:17]1Participants
3
Sources & evidence
- ORD record
- ord-4ae5e60c38c84be48446d79646f32b1e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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