Methyl 5-aminobenzofuran-2-carboxylate → N4-(3-tert-butylphenyl)-5-fluoro-N2-(2-methoxycarbonylbenzofur-5-yl)-2,4-pyrimidinediamine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:11][c:12]2[n:13][c:14]([Cl:19])[n:15][cH:16][c:17]2[F:18])[cH:8][cH:9][cH:10]1.[CH3:20][O:21][C:22](=[O:23])[c:24]1[o:25][c:26]2[c:27]([cH:28]1)[cH:29][c:30]([NH2:33])[cH:31][cH:32]2>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:11][c:12]2[n:13][c:14]([NH:33][c:30]3[cH:29][c:27]4[c:26]([o:25][c:24]([C:22]([O:21][CH3:20])=[O:23])[cH:28]4)[cH:32][cH:31]3)[n:15][cH:16][c:17]2[F:18])[cH:8][cH:9][cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-30331c55073441318667b698c59bfaed
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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