Acetic Acid → 1-(4'-(6-Carbamoyl-3,5-dimethylpyrazin-2-yl)-2,6-difluorobiphenyl-4-yl)cyclopropanecarboxylic acid
Reaction equation
[C:3]([NH2:4])(=[O:5])[c:6]1[c:7]([CH3:34])[n:8][c:9]([CH3:33])[c:10](-[c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19]([F:32])[cH:20][c:21]([C:25]4([C:28](=[O:29])[O:30][CH3:31])[CH2:26][CH2:27]4)[cH:22][c:23]3[F:24])[cH:16][cH:17]2)[n:11]1.[CH3:35][C:36](=[O:37])[OH:38].[CH3:42][C:43]([OH:44])([CH3:45])[CH3:46].[CH3:47][CH2:48][OH:49].[CH3:50][OH:51].[Cl:39][CH2:40][Cl:41].[K+:2].[OH-:1]>>[C:3]([NH2:4])(=[O:5])[c:6]1[c:7]([CH3:34])[n:8][c:9]([CH3:33])[c:10](-[c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19]([F:32])[cH:20][c:21]([C:25]4([C:28](=[O:29])[OH:30])[CH2:26][CH2:27]4)[cH:22][c:23]3[F:24])[cH:16][cH:17]2)[n:11]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-4bfcfdef6aa5441ab16353b5017d50a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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