Sodium ion → tert-butyl 5-(3-(4-(1H-pyrazol-4-yl)phenoxy)propyl)-2-(8-(benzo[d]thiazol-2-yl((2-(trimethylsilyl)ethoxy)methyl)carbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylate
Reaction equation
[C:68](=[O:69])([O-:70])[O-:71].[CH3:54][C:55]1([CH3:56])[C:57]([CH3:58])([CH3:59])[O:60][B:61]([c:62]2[cH:63][n:64][nH:65][cH:66]2)[O:67]1.[Na+:72].[Na+:73].[s:1]1[c:2]([N:10]([C:11](=[O:12])[c:13]2[cH:14][cH:15][cH:16][c:17]3[c:22]2[CH2:21][N:20]([c:23]2[s:24][c:25]([CH2:35][CH2:36][CH2:37][O:38][c:39]4[cH:40][cH:41][c:42]([I:45])[cH:43][cH:44]4)[c:26]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[n:27]2)[CH2:19][CH2:18]3)[CH2:46][O:47][CH2:48][CH2:49][Si:50]([CH3:51])([CH3:52])[CH3:53])[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[s:1]1[c:2]([N:10]([C:11](=[O:12])[c:13]2[cH:14][cH:15][cH:16][c:17]3[c:22]2[CH2:21][N:20]([c:23]2[s:24][c:25]([CH2:35][CH2:36][CH2:37][O:38][c:39]4[cH:40][cH:41][c:42](-[c:62]5[cH:63][nH:64][n:65][cH:66]5)[cH:43][cH:44]4)[c:26]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[n:27]2)[CH2:19][CH2:18]3)[CH2:46][O:47][CH2:48][CH2:49][Si:50]([CH3:51])([CH3:52])[CH3:53])[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-cbe95ce6f30048a992984197a7ee17c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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