Toluene → 5-Bromo-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline
Reaction equation
[Br:1][c:2]1[c:3]([CH2:4][CH2:5][NH:6][C:7]([c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)=[O:18])[cH:19][cH:20][cH:21][cH:22]1.[CH3:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1>>[Br:1][c:2]1[c:3]2[c:19]([cH:20][cH:21][cH:22]1)[C:7]([c:8]1[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1)=[N:6][CH2:5][CH2:4]2Participants
3
Sources & evidence
- ORD record
- ord-d5e43e610f374b3a8be31b11cb6faae2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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