1-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrile → Methyl 4-[2-(4-aminopiperidin-1-yl)ethyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylate

HRID 690249Notes

Reaction equation

HRID 690249 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][CH:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]2[C:18](=[O:31])[CH2:19][O:20][c:21]3[c:22]2[cH:23][c:24]([C:27](=[O:28])[O:29][CH3:30])[cH:25][cH:26]3)[CH2:13][CH2:14]1)([CH3:5])([CH3:6])[CH3:7].[NH2:32][CH:33]1[CH2:34][CH2:35][N:36]([CH2:37][CH2:38][n:39]2[c:40]3[c:41]([cH:42][cH:43][c:44]([C:45]#[N:46])[cH:47]3)[cH:48][cH:49][c:50]2=[O:51])[CH2:52][CH2:53]1>>[NH2:8][CH:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]2[C:18](=[O:31])[CH2:19][O:20][c:21]3[c:22]2[cH:23][c:24]([C:27](=[O:28])[O:29][CH3:30])[cH:25][cH:26]3)[CH2:13][CH2:14]1

Participants

3

Reactant 2

HCID 602009201-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrileHCID 66774852Methyl 4-(2-{4-[(tert-butoxycarbonyl)amino]piperidin-1-yl}ethyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylate

Product 1

HCID 66774773Methyl 4-[2-(4-aminopiperidin-1-yl)ethyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylate

Sources & evidence

ORD record
ord-a1101baa4b5041e2840cb946144f596c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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