2-Chloro-4-hydroxybenzonitrile → HCID 46701320, compound

HRID 690260Notes

Reaction equation

HRID 690260 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][N:8]([c:12]1[n:13][c:14]([NH2:25])[n:15][c:16]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[cH:17]1)[CH2:7][CH2:6]2.[Cl:26][c:27]1[c:28]([C:29]#[N:30])[cH:31][cH:32][c:33]([OH:35])[cH:34]1>>[c:2]1([O:35][c:33]2[cH:32][cH:31][c:28]([C:29]#[N:30])[c:27]([Cl:26])[cH:34]2)[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][N:8]([c:12]1[n:13][c:14]([NH2:25])[n:15][c:16]([N:18]3[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]3)[cH:17]1)[CH2:7][CH2:6]2

Participants

3

Reactant 2

HCID 5927972-Chloro-4-hydroxybenzonitrileHCID 467010484-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine

Product 1

HCID 46701320HCID 46701320, compound

Sources & evidence

ORD record
ord-77aff0bb30ce4580a97dbd196e762161
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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