Acetonitrile → N-[[3-[3-fluoro-4-[4-(pyrimidin-2-ylsulfanylmethyl)imidazol-1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HRID 690326Notes

Reaction equation

HRID 690326 reaction equation
[CH2:33]([O:34][CH:35]([O:36][CH2:37][C:38]([CH3:39])([CH3:40])[CH3:41])[N:42]([CH3:43])[CH3:44])[C:45]([CH3:46])([CH3:47])[CH3:48].[CH3:49][C:50]#[N:51].[F:1][c:2]1[cH:3][c:4]([N:15]2[C:16](=[O:25])[O:17][CH:18]([CH2:20][NH:21][C:22]([CH3:23])=[O:24])[CH2:19]2)[cH:5][cH:6][c:7]1-[n:8]1[cH:9][n:10][c:11]([CH2:13][OH:14])[cH:12]1.[nH:26]1[c:27](=[S:32])[n:28][cH:29][cH:30][cH:31]1>>[F:1][c:2]1[cH:3][c:4]([N:15]2[C:16](=[O:25])[O:17][CH:18]([CH2:20][NH:21][C:22]([CH3:23])=[O:24])[CH2:19]2)[cH:5][cH:6][c:7]1-[n:8]1[cH:9][n:10][c:11]([CH2:13][S:32][c:27]2[n:26][cH:31][cH:30][cH:29][n:28]2)[cH:12]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 786231,1-Bis(2,2-dimethylpropoxy)-N,N-dimethylmethanamineHCID 15504892-MercaptopyrimidineHCID 18378806N-{3-[3-Fluoro-4-(4-hydroxymethyl-imidazol-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

Product 1

HCID 9824616N-[[3-[3-fluoro-4-[4-(pyrimidin-2-ylsulfanylmethyl)imidazol-1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Sources & evidence

ORD record
ord-a2c70888db8f4413a41edd3ebe20ba35
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…