Boron tribromide → [4-(2-Azepan-1-yl-ethoxy)-phenyl]-[2-(2,4-difluoro-phenyl)-6-hydroxy-naphthalen-1-yl]-methanone
Reaction equation
[B:75]([Br:76])([Br:77])[Br:78].[F:1][c:2]1[cH:3][c:4]([F:5])[cH:6][cH:7][c:8]1-[c:9]1[cH:10][cH:11][c:12]2[c:13]([cH:14][cH:15][c:16]([OH:17])[cH:18]2)[c:19]1[C:20]([c:21]1[cH:22][cH:23][c:24]([O:25][CH2:26][CH2:27][N:28]2[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]2)[cH:34][cH:35]1)=[O:36].[N:37]1([CH2:44][CH2:45][O:46][c:47]2[cH:48][cH:49][c:50]([C:53](=[O:54])[c:55]3[c:56](-[c:67]4[c:68]([F:74])[cH:69][c:70]([F:73])[cH:71][cH:72]4)[cH:57][cH:58][c:59]4[cH:60][c:61]([O:65][CH3:66])[cH:62][cH:63][c:64]34)[cH:51][cH:52]2)[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]1>>[N:37]1([CH2:44][CH2:45][O:46][c:47]2[cH:48][cH:49][c:50]([C:53](=[O:54])[c:55]3[c:56](-[c:67]4[c:68]([F:74])[cH:69][c:70]([F:73])[cH:71][cH:72]4)[cH:57][cH:58][c:59]4[cH:60][c:61]([OH:65])[cH:62][cH:63][c:64]34)[cH:51][cH:52]2)[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0647b12c8d6f4905818cccad42406089
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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