Ethanol → 4-Chloro-2-[[(2,3-difluorophenyl)methyl]thio)-6-ethoxy-pyrimidine

HRID 690393Notes

Reaction equation

HRID 690393 reaction equation
[CH3:21][CH2:22][OH:23].[Cl:1][c:2]1[n:3][c:4]([S:9][CH2:10][c:11]2[c:12]([F:18])[c:13]([F:17])[cH:14][cH:15][cH:16]2)[n:5][c:6]([Cl:8])[cH:7]1.[H-:19].[Na+:20].[OH2:24]>>[c:2]1([O:23][CH2:22][CH3:21])[n:3][c:4]([S:9][CH2:10][c:11]2[c:12]([F:18])[c:13]([F:17])[cH:14][cH:15][cH:16]2)[n:5][c:6]([Cl:8])[cH:7]1

Participants

6

Reactant 5

HCID 702EthanolHCID 923Sodium ionHCID 962WaterHCID 166653HydrideHCID 859280374,6-Dichloro-2-((2,3-difluorobenzyl)thio)pyrimidine

Product 1

HCID 866198724-Chloro-2-[[(2,3-difluorophenyl)methyl]thio)-6-ethoxy-pyrimidine

Sources & evidence

ORD record
ord-aaa84fba50a84118bd5317e981a3e0b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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