2-[(1,1-Dimethyl-prop-2-ynyl)-methyl-amino]-ethanol → 2-({3-[1-(4-Fluoro-phenyl)-1H-indol-5-yl]-1,1-dimethyl-prop-2-ynyl}-methyl-amino)-ethanol

HRID 690424Notes

Reaction equation

HRID 690424 reaction equation
[CH3:25][C:26]([C:27]#[CH:28])([CH3:29])[N:30]([CH2:31][CH2:32][OH:33])[CH3:34].[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][cH:10][c:11]3[cH:12][c:13]([O:17][S:18]([C:19]([F:20])([F:21])[F:22])(=[O:23])=[O:24])[cH:14][cH:15][c:16]23)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][cH:10][c:11]3[cH:12][c:13]([C:28]#[C:27][C:26]([CH3:25])([CH3:29])[N:30]([CH2:31][CH2:32][OH:33])[CH3:34])[cH:14][cH:15][c:16]23)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 186795312-[(1,1-Dimethyl-prop-2-ynyl)-methyl-amino]-ethanolHCID 86585583Trifluoro-methanesulfonic acid 1-(4-fluoro-phenyl)-1H-indol-5-yl ester

Product 1

HCID 186794332-({3-[1-(4-Fluoro-phenyl)-1H-indol-5-yl]-1,1-dimethyl-prop-2-ynyl}-methyl-amino)-ethanol

Sources & evidence

ORD record
ord-81404b9ec77e4a79afb83fa2d475ad19
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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