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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 690644Generated: October 25, 2026

Potassium Cation → Methyl 1-(2-(5-(5-(4-(difluoromethoxy)phenyl)pyrimidin-2-ylamino)-2-fluorophenoxy)ethyl)piperidine-4-carboxylate

https://huagongshe.com/reaction/690644

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
ReactantCarbonate IonHCID 19660—
Reactant1,4-DioxaneHCID 31275—
Reactant2-(4-(Difluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 22032303—
ReactantMethyl 1-(2-(5-(5-bromopyrimidin-2-ylamino)-2-fluorophenoxy)ethyl)piperidine-4-carboxylateHCID 58542307—
ReactantHCID 178420554HCID 178420554—
ProductMethyl 1-(2-(5-(5-(4-(difluoromethoxy)phenyl)pyrimidin-2-ylamino)-2-fluorophenoxy)ethyl)piperidine-4-carboxylateHCID 68729011—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-bd581a1289264b1c8cc389efdf500b82
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)