Dichloromethane → tert-butyl N-[4-[1-(cyclopentanecarbonyl)-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamate

反応式

[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[NH:28][CH:29]([CH2:30][C:31](=[O:32])[OH:33])[CH2:34][c:35]1[c:36]([F:43])[cH:37][c:38]([F:42])[c:39]([F:41])[cH:40]1.[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[CH:1]1([C:6](=[O:7])[c:8]2[n:9][c:10]([C:17]([F:18])([F:19])[F:20])[n:11]3[c:12]2[CH2:13][NH:14][CH2:15][CH2:16]3)[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl:66][CH2:67][Cl:68].[O:51]=[C:52]1[N:53]([P:54]([Cl:55])([N:56]2[CH2:57][CH2:58][O:59][C:60]2=[O:61])=[O:62])[CH2:63][CH2:64][O:65]1>>[CH:1]1([C:6](=[O:7])[c:8]2[n:9][c:10]([C:17]([F:18])([F:19])[F:20])[n:11]3[c:12]2[CH2:13][N:14]([C:31]([CH2:30][CH:29]([NH:28][C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[CH2:34][c:35]2[c:36]([F:43])[cH:37][c:38]([F:42])[c:39]([F:41])[cH:40]2)=[O:32])[CH2:15][CH2:16]3)[CH2:2][CH2:3][CH2:4][CH2:5]1