Methanol → 5-(3-Methylazetidin-1-yl)-2-nitropyridine

HRID 690879Notes

Reaction equation

HRID 690879 reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH2:32]1[O:33][CH2:34][CH2:35][O:36][CH2:37]1.[CH2:40]([Cl:41])[Cl:42].[CH3:11][CH:12]1[CH2:13][NH2+:14][CH2:15]1.[CH3:38][OH:39].[Cs+:30].[Cs+:31].[N+:16](=[O:17])([O-:18])[c:19]1[n:20][cH:21][c:22]([Br:25])[cH:23][cH:24]1.[OH2:43].[c:1]1([S:2]([O-:3])(=[O:4])=[O:5])[cH:6][cH:7][cH:8][cH:9][cH:10]1>>[CH3:11][CH:12]1[CH2:13][N:14]([c:22]2[cH:21][n:20][c:19]([N+:16](=[O:17])[O-:18])[cH:24][cH:23]2)[CH2:15]1

Participants

10

Reactant 9

HCID 887MethanolHCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 91526BenzenesulfonateHCID 104967Cesium cation2×HCID 8176205-Bromo-2-nitropyridineHCID 576628303-Methylazetidin-1-ium

Product 1

HCID 580441445-(3-Methylazetidin-1-yl)-2-nitropyridine

Sources & evidence

ORD record
ord-941df021c1114a22a72d883ac6eb5a45
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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