Picolyl chloride → N-Methyl-N-{2-[(4-{[3-methyl-4-(pyridin-2-ylmethoxy)phenyl]amino}quinazolin-5-yl)oxy]ethyl}acetamide
Reaction equation
[Cl:1][CH2:2][c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1.[OH:9][c:10]1[c:11]([CH3:35])[cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][cH:23][cH:24][c:25]([O:27][CH2:28][CH2:29][N:30]([C:31]([CH3:32])=[O:33])[CH3:34])[c:26]23)[cH:14][cH:15]1>>[CH2:2]([c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([CH3:35])[cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][cH:23][cH:24][c:25]([O:27][CH2:28][CH2:29][N:30]([C:31]([CH3:32])=[O:33])[CH3:34])[c:26]23)[cH:14][cH:15]1Participants
3
Sources & evidence
- ORD record
- ord-75a7eac1d7f3405bad248ee98a1e3f07
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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