Dimethyl Sulfoxide → N-(1,3-Thiazol-2-yl)pyridin-2-amine 19
Reaction equation
[CH3:17][N:18]([C:19](=[O:20])[N:21]1[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1)[CH3:27].[CH3:28][S:29]([CH3:30])=[O:31].[Cl:1][CH2:2][c:3]1[cH:4][c:5]([NH:9][c:10]2[s:11][c:12]([C:15]#[N:16])[cH:13][n:14]2)[n:6][cH:7][cH:8]1.[OH2:32]>>[CH2:2]([c:3]1[cH:4][c:5]([NH:9][c:10]2[s:11][c:12]([C:15]#[N:16])[cH:13][n:14]2)[n:6][cH:7][cH:8]1)[N:24]1[CH2:23][CH2:22][N:21]([C:19]([N:18]([CH3:17])[CH3:27])=[O:20])[CH2:26][CH2:25]1Participants
5
Sources & evidence
- ORD record
- ord-283e1e8408a14dd391f7bce7a5c5d9c4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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