Methanol → Methyl 4-hydroxy-2,2-dimethyl-4-[5-[3-methyl-5-[[4-(trifluoromethyl)pyrimidin-2-yl]amino]phenyl]-1,3-thiazol-2-yl]cyclohexane-1-carboxylate
Reaction equation
[CH3:41][OH:42].[OH2:43].[OH:1][C:2]1([c:13]2[s:14][c:15](-[c:18]3[cH:19][c:20]([CH3:35])[cH:21][c:22]([NH:24][c:25]4[n:26][cH:27][cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[n:30]4)[cH:23]3)[cH:16][n:17]2)[CH2:3][C:4]([CH3:11])([CH3:12])[CH:5]([C:8](=[O:9])[OH:10])[CH2:6][CH2:7]1.[S:36](=[O:37])(=[O:38])([OH:39])[OH:40]>>[OH:1][C:2]1([c:13]2[s:14][c:15](-[c:18]3[cH:19][c:20]([CH3:35])[cH:21][c:22]([NH:24][c:25]4[n:26][cH:27][cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[n:30]4)[cH:23]3)[cH:16][n:17]2)[CH2:3][C:4]([CH3:11])([CH3:12])[CH:5]([C:8]([O:9][CH3:41])=[O:10])[CH2:6][CH2:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-979d259382c84211b754dcae1ab3a099
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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