Sodium ion → 1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-phenyl-ethylamine

HRID 691520Notes

Reaction equation

[Br:1][Mg:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1.[CH3:21][Li:22].[CH3:25][CH2:26][O:27][CH2:28][CH3:29].[CH3:30][CH:31]([CH3:32])[O-:33].[CH3:35][CH:36]([CH3:37])[O-:38].[CH3:39][CH:40]([CH3:41])[O-:42].[CH3:43][CH:44]([CH3:45])[O-:46].[Na+:24].[O:9]1[CH2:10][CH2:11][O:12][C:13]12[CH2:14][CH2:15][CH:16]([C:19]#[N:20])[CH2:17][CH2:18]2.[OH-:23].[Ti+4:34]>>[c:3]1([C:19]([CH:16]2[CH2:15][CH2:14][C:13]3([O:9][CH2:10][CH2:11][O:12]3)[CH2:18][CH2:17]2)([NH2:20])[CH3:21])[cH:4][cH:5][cH:6][cH:7][cH:8]1

Participants

Reactant 8

HCID 923Sodium ion

HCID 961Hydroxide

HCID 3283Diethyl Ether

HCID 114942Titanium cation (4+)

HCID 3260420Isopropanolate4×

HCID 111164331,4-Dioxaspiro[4.5]decane-8-carbonitrile

HCID 178418255HCID 178418255, compound

HCID 178418348HCID 178418348, compound

Product 1

HCID 583810151-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-phenyl-ethylamine

Sources & evidence

ORD record: ord-b5a32369bcc84a129396ebfddd1f9f31
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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